inhibit相关论文
In this study, inhibition of tall oil fatty acid hydrodeoxygenation (HDO) activity due to addition of rosin acid over su......
Pygopus-2 promotes invasion and metastasis of hepatic carcinoma cell by decreasing E-cadherin expres
Pygopus-2 over-expression has been reported in several malignancies,such as ovarian,breast,lung and liver cancers.Here w......
Triple administration of osimertinib followed by chemotherapy for advanced lung adenocarcinoma: A ca
BACKGROUND Osimertinib is the recommended first-line treatment for adult patients with epidermal growth factor receptor(......
Multiple myeloma (MM) is a uniformly fatal disease characterized by a clonal proliferation of neoplastic plasma cells in......
The mixtures of α-quartz and graphite powder with different mass ratios were, respectively, high-energetically mechanic......
Down-regulation of survivin expression by small interfering RNA induces pancreatic cancer cell apopt
AIM: To investigate the inhibitory effect of small interfering RNA (siRNA) on the expression of survivin in pancreatic c......
With the many changes that have taken place in people’ s diet and lifestyle, colorectal cancer (CRC) has become a globa......
Anti-hepatoma activity and mechanism of ursolic acid and its derivatives isolated from Aralia decais
AIM:To investigate the anti-tumor activity of ursolic acid(UA)and its derivatives isolated from Aralia decaisneanaon he......
AIM: To investigate the effects of activated rat hepatic stellate cells(HSCs) on rat Th1/Th2 profile in vitro.METHODS: G......
厌氧氨氧化为高效低耗生物脱氮技术,但金属元素对该工艺的作用存在两面性,一方面其促进作用可提高工艺处理效果,另一方面抑制作用......
The Effect of Interleukin-6 on the Proliferation of Prostate Cancer Cells in Vitro and the Modulatio
The role of interleukin-6 (IL-6) in the growth of an androgen-independent prostate cancer cell line (PC-3m) was defined ......
AIM:To investigate the correlation between gastric cancer growth and signal transducer and activator of transcription-3(......
Objective:The aim of the study was to explore the activities of cis9,trans11-CLA(C9,t11-CLA) and trans10,cis12-CLA(t10,c......
HERBAL MEDICINE 960 RECIPE REGULATES THE PROLIFERATION AND APOPTOSIS OF HUMAN HEPATOMA CELL LINE SMM
To investigate the mechanism of 960 recipe regulating the proliferation and apoptosis of human hepatoma SMMC7721 cells.......
Objective: Tea polyphenols present in green tea show cancer chemopreventive effects in many tumor models. Epidemiologica......
硫磺有杀虫、杀螨和杀菌作用。很多卫生筷用硫磺熏,是为了起到漂白 的作用,这样可以使筷子看起来更白,更干净。但是,硫磺燃烧后会......
Synthesis of polyethylenimine grafted with copolymers of polyethylene glycol and polycaprolactone an
Copolymers mPEG-PCL were prepared and grafted onto polyethylenimine(PEI) to synthesize copolymers mPEG-PCL-g-PEI with lo......
Influence of silicon and carbon elements on formation of 1:13 phase and microstructure in LaFe_(13-y
Microstructure dependent on silicon and formation of 1:13 phase in LaFe13-ySiyC0.2 compounds was investigated. C and Si ......
Identification of Herbal Compound Imperatorin with Adverse Effects on ANO1 and CFTR Chloride Channel
Calcium-activated chloride channels(CaCCs) are the crucial regulators of transepithelial fluid secretion, smooth muscle ......
Roles of polyacrylate dispersant in the synthesis of well-dispersed BaSO_4 nanoparticles by simple p
Well-dispersed BaSO_4 nanoparticles were synthesized in the presence of sodium polyacrylate(PAAS) by a simple precipitat......
A series of novel glyco-gambogic acid(GA) compounds were synthesized and evaluated for their in vitro anti-proliferative......
Purification and in vitro Activity of an Antimicrobial Peptide from Skin of Rana Temporaria Chensine
In this study,an antimicrobial component(RTCI)was purified from the skin of Rana temporaria chensinensis,David.Antimicro......
Histone deacetylases(HDACs) are considered to be among the most promising targets for the development of anti-cancer dru......
Chitosan-montmorillonite is a modified montmorillonite in which the sodium ions in montmorillonite layers are replaced b......
Objective To study the effects of melatonin on pethidine-induced physical dependence and its antioxidative action.Method......
Anti-diarrheal and spasmolytic activities study of 3,4-Dihydro-2-(4-Morpholinylmethy)-1(2H)-Naphthal
Objective To investigate the spasmolytic and anti-diarrheal activities of 3,4-dihydro-2-(4-morpholinylmethy)-1(2H)-napht......
Albaconol,a Plant-Derived Small Molecule,Inhibits Macrophage Function by Suppressing NF-κB Activatio
Discovery and functional identification of plant-derived small compounds as the immunosuppressant attract much attention......
Effects of Pulsed Magnetic Field on Biochemical and Physiological Characters and Ultrastructure of P
In this paper,we employed the pulsed magnetic field(PMF) processing to investigate the effect of different pulse rise ti......
In this research,an unusually dimeric G-quadruplex of d(GGGTGGGTGGGTGGGT)(S1),the potent nanomolar HIV-1 integrase inhib......
Structure-based design of conformationally constrained cyclic peptidomimetics to target the MLL1-WDR
We described herein structure-based design,synthesis and evaluation of conformationally constrained,cyclic peptidomimeti......
Objective To explore the antitumor effect of Yuyihe Powder(Yu Yi He San,YYHS) and its antitumor mechanism.Methods After ......
The risk of cardiovascular disease increases along with aging. There are increasing interests in researches on the prote......
Synthesis and in vitro biological evaluation of nitric oxide-releasing derivatives of hydroxylcinnam
Novel furoxan-based nitric oxide-releasing derivatives 6a-p of hydroxylcinnamic acids were synthesized by coupling the c......
Multi-target agents against tyrosine kinases and topoisomerases are potentially useful for the effective treatment of ca......
Synthesis and Biological Activities of 10-Substituted 9-Aryl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5
A series of 10-substituted 9-aryl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione derivatives 2 were synthesized by a tw......
Dilazep and dipyridamole inhibit tissue factor expressionon monocytes induced by IgG from patientswi
AIM: To investigate whether antiplatelet agents, dilazep and dipyridamole, inhibit tissue factor (TF) expression on mono......
The cellular labeling and pH-sensitive responsive-drug release of celastrol in cancer cells based on
As one of the active compounds derived from Traditional Chinese Medicine,Celastrol(CSL)had cytotoxicity for human leukem......
OBJECTIVE Geldanamycin,a natural product of Streptomyces geldanus,binds the heat shock protein 90(Hsp90),a cell chaperon......
Effects of simvastatin on lipid levels and platelet activation in elderly patients with hypercholest
Background and Objective To investigate the effects of simvastatin on lipid lowering therapy and platelet activation in ......
Advanced glycation end products inhibit production and activity of matrix metalloproteinase-2 in hum
Objective It has been reported that advanced glycation end products (AGEs) participate in pathogenesis of accelerated at......
Enhanced antibacterial activity of silica nanorattles with ZnO combination nanoparticles against met
Silica nanorattles(SNs) with zinc oxide(ZnO) combination nanoparticles are reported to inhibit methicillin-resistant Sta......
Increased expression of osteoprotegerin in vascular smooth muscle cells from spontaneously hypertens
Osteoprotegerin (OPG) is a secreted protein of the tumor necrosis factor receptor family,whichregulates bone mass by in......
Effect of simulated ischemia-reperfusion on I_f in sinoatrial node cells and the intervention of KAT
Objective: To study the effect of simulated ischemia-reperfusion (I/R) on If of sinoatrial node (SAN) cells and the inte......
Mesenteric artery remodeling and effects of imidapril and irbesartan on it in spontaneously hyperten
AIM: To investigate the remodeling of mesenteric arteryand the expression of TGF-β_1,c-Jun in mesenteric arteryand eff......
Bioactivity-based UPLC/Q-TOF/MS strategy for screening of anti-inflammatory components from Cimicifu
In this study,the protective effects of Cimicifugae Rhizoma(CR) was demonstrated in Pseudomonas aeruginosa-induced pneum......
A novel series of β-propanamide derivatives as inhibitors of cholesteryl ester transfer protein(CETP)were synthesized.P......
Objective To investigate whether the calcium channel blocker amlodipine could inhibit macrophage matrix metalloproteinas......
Aim:To test the hypothesis that statins inhibit leptin-induced hypertrophy incultured neonatal rat cardiomyocytes.Metho......
Implication of Receptor Activator of NF-κB Ligand in Wnt/β-Catenin Pathway Promoting Osteoblast-like
Recent studies showed that activation of Wnt/β-catenin pathway promoted the differentiation of osteoblast-like cells in......
